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Page: 224
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ISBN: 9780262551359
Publisher: MIT Press
How a small number of risky experiments creates many unwieldy problems for life science research.
The life sciences have never been more critical to human health, wealth, and security. But with any endeavor comes risk, and the last decade has seen concerns raised about gain-of function-research in which a microbe, usually a virus, is given new properties like enhanced lethality, transmissibility, or the capability to infect new species. In 2021 the term seeped into the tabloids when a conflict between Senator Rand Paul and Dr. Anthony Fauci arose over the origins of COVID-19. In Gain of Function, Nicholas Evans—who has spent his career studying gain-of-function research—describes what this kind of research is, what it isn’t, and why a small number of scientific experiments continues to make headlines.
Evans begins with a description of what gain-of-function research is in science, and what it means in government policy. He tells the story of the original papers that sparked controversy more than a decade ago, unpacking them for readers unfamiliar with virology research, and he identifies where and why policymakers and scientists alike became concerned. He then turns to the history of policies that attempt to regulate gain-of-function research, the current controversies, and the ethics of risky research. He concludes with the future of gain of function, including how debates about gain of function will influence science and public health in years to come.
Gain of function mutation – Knowledge and References
The research on this page is brought to you by Taylor & Francis Knowledge Centers. This collection is automatically generated from our most recent books and .
Gain of Function Controversy Demands Greater Scrutiny for .
Gain of function research aims to genetically alter microorganisms to enhance certain biological properties. For example, recent gains of .
What Is Gain of Function? - MIT Press Direct
1: What Is Gain of Function? . This content is PDF only. Please click on the PDF icon to access. Open the Chapter PDF for in another window.
Trump freezes 'gain of function' pathogen research - Nature
An executive order suspends the use of federal funds for certain experiments on pathogens with pandemic potential.
U.S. Government Gain-of-Function Deliberative Process and .
Selected Gain-of-Function Research Involving Influenza, MERS, and SARS Viruses. Gain-of-function studies, or research that improves the .
International community 'complicit' in gain-of-function research: book
The National Institutes of Health (NIH) came under fire this week after it admitted to funding gain-of-function research on the coronavirus .
'Viral' book promotes COVID-19 lab-leak theory erroneously
gain-of-function experiments) — and ultimately to the proposition that researchers at the institute unwittingly became infected while doing .
Understanding Gain-of-Function Research: Implications of Trump's .
An in-depth analysis of gain-of-function research, its historical controversies, connection to COVID-19 origins debate, and the significant .
Gain-of-Function Research, National Academies, eBook, PDF - BUKU
A public symposium on potential US government policies for the oversight of gain-of-function (GOF) research.
Gain of Function, Evans, Nicholas - Galena Book & Paper
Gain of Function, Evans, Nicholas. $16.95. 1. Only 1 remaining. Add to Cart . Book & Paper. © 2025. Powered by Square.
Trump Executive Order Restricts 'Gain of Function' Research on .
For over a decade, scientists have debated the risks and benefits of so-called “gain of function” research. Book Review · Best Sellers Book .
Gain-of-function and origin of Covid19 - ScienceDirect.com
This is true not only when dealing with emerging Potentially Pandemic Pathogens (PPP), such as influenza viruses or coronaviruses, but also with low pathogenic .
[PDF] Gain-of-Function Research: Ethical Analysis
Gain-of-function (GOF) research involves experimentation that aims or is expected to (and/or, perhaps, actually does) increase the transmissibility and/or .
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